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  1. Epigenetics JAK/STAT Signaling TGF-beta/Smad
  2. Pim PKC
  3. Pim-1 kinase inhibitor 8

Pim-1 kinase inhibitor 8 

目录号: HY-162006
产品使用指南

Pim-1 kinase inhibitor 8 (compound 12) 是 Pim-1 kinase 的有效抑制剂,其 IC50 为 14.3 nM。Pim-1 kinase inhibitor 8 对 MCF-7 和 HepG2 细胞具有较强的细胞毒性,其 IC50 分别为 0.5 和 5.27 μM。Pim-1 kinase inhibitor 8 可用于乳腺癌研究。

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Pim-1 kinase inhibitor 8 Chemical Structure

Pim-1 kinase inhibitor 8 Chemical Structure

CAS No. : 916038-47-6

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生物活性

Pim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC50 of 14.3 nM. Pim-1 kinase inhibitor 8 has potent cytotoxicity against MCF-7 and HepG2 cells with IC50s of 0.5 and 5.27 μM, respectively. Pim-1 kinase inhibitor 8 can used in study breast cancer[1].

分子量

275.30

Formula

C14H17N3O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Pim-1 kinase inhibitor 8 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pim-1 kinase inhibitor 8
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HY-162006
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